Theme Member
Chee Man Cheong

Contact Details

Phone: +61 08 8128 4694

Email: chee.m.cheong@adelaide.edu.au

LinkedIn: https://www.linkedin.com/in/cheemancheong

Qualifications:

Bachelor of Science (Biomedicine), University of Adelaide

Bachelor of Health Sciences (Honours, First Class), University of Adelaide

Biography/Research Focus

Localised solid tumour cells metastases to secondary site via a series of phenotypic and gene expression changes known as epithelial-to-mesenchymal transition (EMT), resulting in a motile and invasive phenotype. Although “metastasis” and “EMT” are not commonly used to describe the dissemination of haematological malignancies, recent studies from our laboratory showed that high-risk t(4;14) multiple myeloma (MM) patients express an EMT-like gene signature, suggesting a role for EMT in MM. My PhD project will determine major regulatory events leading to EMT-like programme in the dissemination of MM and will identify ideal therapeutic targets to control the spread of MM in high-risk patients with aggressive disease.

Publications

Cheong CM, Chow AW, Fitter S, Hewett DR, Martin SK, Williams SA, To LB, Zannettino AC, Vandyke K. Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo. Experimental Cell Research. 2015; 332(1):24-38

Awards/Funding

2013 PhD Scholarship, Adelaide Graduate Research Scholarship

2011 Summer Research Scholarship, Centre for Stem Cell Research 

Get in touch
+61 8 8128 4000 info@sahmri.com
You can't miss us!
North Terrace Adelaide 5000 South Australia
Postal Address
PO BOX 11060 Adelaide 5001 South Australia
Key Partners
SAHMRI is located on the traditional lands of the Kaurna Nation.

The SAHMRI community acknowledges and respects the traditional owners, the family clans who are the Kaurna Nation from the Adelaide Plains region of South Australia. We acknowledge the clans of the Kaurna Nation and the sacred knowledge they hold for their country. We pay our respects to the Kaurna Nation, their ancestors and the descendants of these living family clans today.