Phone: 08 8128 4367
Bachelor of Science, University of Adelaide
Bachelor of Science (Hons), University of Adelaide
My research is studying the interplay between lipids and prostate cancer cells. Specifically, my work investigates how lipids affect prostate cancer cell growth and death, the effect of lipids on prostate cancer cell responses to drugs and the regulation of lipid biosynthesis by androgen hormones, which are the main driver of prostate cancer cell growth. This work will help us know more about how lipids can be used as biomarkers of tumour aggressiveness and treatment response in prostate cancers.
Publications (since 2010)
- Ochnik AO, Moore NL, Jankovic-Karasoulos T, Bianco-Miotto T, Ryan NK, Thomas MR, Birrell SN, Butler LM, Tilley WD and Hickey TE. The anti-androgenic actions of medroxyprogesterone acetate in epithelial cells within normal human breast tissues cultured ex vivo. Menopause 21: 79-88, 2014.
- Chiam K, Ryan NK, Ricciardelli C, Day TK, Buchanan G, Ochnik AM, Murti K, Selth LA, Australian Prostate Cancer BioResource, Butler LM, Tilley WD and Bianco-Miotto T. Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers. Prostate 73:182-93, 2013.
- Bianco-Miotto T, Chiam K, Buchanan G, Jindal S, Day TK, Thomas M, Pickering MA, O'Loughlin MA, Ryan NK, Raymond WA, Horvath LG, Kench JG, Stricker PD, Marshall VR, Sutherland RL, Henshall SM, Gerald WL, Scher HI, Risbridger GP, Clements JA, Butler LM, Tilley WD, Horsfall DJ, Ricciardelli C; Australian Prostate Cancer BioResource. Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development. Cancer Epidemiol Biomarkers Prev. 19:2611-2622, 2010.