Key Publications (pre-2009)

IMPORTANT PUBLICATIONS (pre-2009)

  1. White D, Saunders V, Lyons A, Branford S, Grigg A, To L, Hughes T. In vitro sensitivity to imatinib-induced inhibition of ABL kinase activity is predictive of molecular response in patients with de novo CML. 2005. Blood 106:2520-2526 IF: 9.06
  2. White DL, Saunders VA, Dang P, Engler J, Zannettino AC, Cambareri AC, Quinn SR, Manley PW, Hughes TP. OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. 2006. Blood 108:697-704 IF: 9.06
  3. White D, Saunders V, Grigg A, Arthur C, Filshie R, Leahy MF, Lynch K, To LB, Hughes T. Measurement of in vivo BCR-ABL kinase inhibition to monitor imatinib-induced target blockade and predict response in chronic myeloid leukemia. 2007. Journal of Clinical Oncology 25:4445-4451 IF: 18.04
  4. White DL, Saunders VA, Dang P, Engler J, Venables A, Zrim S, Zannettino A, Lynch K, Manley PW, Hughes T. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity. 2007. Blood 110:4064-4072 IF: 9.06
  5. Hiwase DK, Saunders V, Hewett D, Frede A, Zrim S, Dang P, Eadie L, To LB, Melo J, Kumar S, Hughes TP, White DL. Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications. 2008. Clinical Cancer Research 14:3881-3888 IF: 7.8
  6. Mullighan CG, Miller CB, Radtke I, Phillips LA, Dalton J, Ma J,White D, Hughes TP, Le Beau MM, Pui CH, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. 2008. Nature 453:110-114 IF: 38.59
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+61 8 8128 4000 info@sahmri.com
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North Terrace Adelaide 5000 South Australia
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PO BOX 11060 Adelaide 5001 South Australia
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SAHMRI is located on the traditional lands of the Kaurna Nation.

The SAHMRI community acknowledges and respects the traditional owners, the family clans who are the Kaurna Nation from the Adelaide Plains region of South Australia. We acknowledge the clans of the Kaurna Nation and the sacred knowledge they hold for their country. We pay our respects to the Kaurna Nation, their ancestors and the descendants of these living family clans today.