Theme Member
Rhys Fogarty

Contact

Phone: 08 8128 4707

Email: rhys.fogarty@sahmri.com

Qualifications

Bachelor of Biotechnology (Hons)

Biography

Rhys completed an Honours degree in Biotechnology at Flinders University of South Australia and has since worked in a diverse range of research areas. At the Centre for Hormone Research, Murdoch Childrens Research Institute in Melbourne he helped develop a novel gene inhibitory drug for psoriasis. He has conducted research into the biology of henipaviruses at the Australian Animal Health Laboratory (CSIRO) in Geelong as part of an international consortium investigating the factors responsible for the spillover of these viruses into humans and domestic animals. In the Department of Ophthalmology at Flinders University he studied the molecular genetics of complex ocular diseases including glaucoma and diabetic retinopathy and applied proteomics techniques to determine the molecular basis of retinopathy of prematurity, a blinding eye condition of premature infants.

Publications

Cheng CY, Schache M, Ikram MK,et al. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet. 2013 Aug 8;93(2):264-77.

Kaidonis G, Abhary S, Daniell M, Gillies M, Fogarty R, Petrovsky N, Jenkins A, Essex R, Chang JH, Pal B, Hewitt AW, Burdon KP, Craig JE. Genetic study of diabetic retinopathy: recruitment methodology and analysis of baseline characteristics. Clin Experiment Ophthalmol. 2013 Sep 30.

Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, et al. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet. 2013 Mar;45(3):314-8.

Fogarty RD, Abhary S, Javadiyan S, Kasmeridis N, Petrovsky N, Whiting MJ, Craig JE, Burdon KP. Relationship between DDAH gene variants and serum ADMA level in individuals with type 1 diabetes. J Diabetes Complications. 2012 May-Jun;26(3):195-8.

Halpin K, Hyatt AD, Fogarty R, Middleton D, Bingham J, Epstein JH, Rahman SA, Hughes T, Smith C, Field HE, Daszak P; Henipavirus Ecology Research Group. Pteropid bats are confirmed as the reservoir hosts of henipaviruses: a comprehensive experimental study of virus transmission. Am J Trop Med Hyg. 2011 Nov;85(5):946-51.

Khan K, Rudkin A, Parry DA, Burdon KP, McKibbin M, Logan CV, Abdelhamed ZI, Muecke JS, Fernandez-Fuentes N, Laurie KJ, Shires M, Fogarty R, Carr IM, Poulter JA, Morgan JE, Mohamed MD, Jafri H, Raashid Y, Meng N, Piseth H, Toomes C, Casson RJ, Taylor GR, Hammerton M, Sheridan E, Johnson CA, Inglehearn CF, Craig JE, Ali M. Homozygous mutations in PXDN cause congenital cataract, corneal opacity, and developmental glaucoma. Am J Hum Genet. 2011 Sep 9;89(3):464-73.

Tea M, Fogarty R, Brereton H, Michael M, Van der Hoek M, Tsykin A, Coster D, Williams K. (2009). Gene expression microarray analysis of early oxygen-induced retinopathy in the rat. Journal of Ocular Biology, Diseases and Informatics. 2(4): 190-201.

Fogarty R, Halpin K, Hyatt AD, Daszak P and Mungal, BA. (2008). Henipavirus susceptibility to environmental variables. Virus Research. 132(1-2):140-144.

Fogarty RD, McKean SC, White PJ, Werthe, GA and Wraight CJ. (2002). Sequence dependence of C5-propynyl-dU, dC-phosphorothioate oligonucleotide inhibition of the human IGF-I receptor: mRNA, protein and cell growth. Antisense and Nucleic Acid Drug Development. 12(6):369-377.

White PJ, Gray AC, Fogarty RD, Sinclair RD, Thumiger SP, Werther GA and Wraight CJ. (2002). C-5 propyne-modified oligonucleotides penetrate the epidermis in psoriatic and not normal human skin after topical application. J Invest Dermatol. 118(6):1003-1007.

Wraight CJ, White PJ, McKean SC, Fogarty RD, Venables DJ, Liepe IJ, Edmondson SE and Werther GA. (2000). Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides. Nature Biotechnology 18(5):521-526.

White PJ, Fogarty RD, Werther GA and Wraight CJ. (2000). Antisense inhibition of IGF receptor expression in HaCaT keratinocytes: a model for antisense strategies in keratinocytes. Antisense and Nucleic Acid Drug Development 10:195-203.

White PJ, Fogarty RD, McKean SC, Venables DJ, Werther GA and Wraight CJ. (1999). Oligonucleotide uptake in cultured keratinocytes: influence of confluence, cationic liposomes, and keratinocyte cell type. Journal of Investigative Dermatology 112(5):699-705.

White PJ, Fogarty RD, Liepe IJ, Delaney PM, Werther GA and Wraight CJ. (1999). Live confocal microscopy of oligonucleotide uptake by keratinocytes in human skin grafts on nude mice. Journal of Investigative Dermatology 112(6):887-892.

Research interests

Psychiatric genetics, neuropsychopharmacology, molecular genetics of complex disease, ophthalmic disease.

Get in touch
+61 8 8128 4000 info@sahmri.com
You can't miss us!
North Terrace Adelaide 5000 South Australia
Postal Address
PO BOX 11060 Adelaide 5001 South Australia
Key Partners
SAHMRI is located on the traditional lands of the Kaurna Nation.

The SAHMRI community acknowledges and respects the traditional owners, the family clans who are the Kaurna Nation from the Adelaide Plains region of South Australia. We acknowledge the clans of the Kaurna Nation and the sacred knowledge they hold for their country. We pay our respects to the Kaurna Nation, their ancestors and the descendants of these living family clans today.