Centre for Nutrition and Gastrointestinal Disease Research

People within this group
Current Research Focus

Our research interests currently include:

Gastrointestinal Vagal Afferent Research

  • Plasticity of GVAs
  • Circadian control of peripheral gastric satiety signals
  • Role of TRPV1 in the regulation of energy balance
  • Estrogen in the regulation of gastric vagal afferent activity
  • Modulation of vagal afferent function in the upper gastrointestinal tract

Obesity and Molecular Metabolism

  • The role of intermittent fasting in improving metabolic health in overweight humans, and to determine whether weight loss is necessary for these benefits.
  • How overfeeding diets contribute to metabolic dysfunction in obesity, with a particular focus on adipose tissue remodelling, skeletal muscle plasticity and oxidative stress.
  • Whether 6 minutes of high intensity exercise can block the metabolic consequences of overfeeding diets in humans.
  • How hyperbaric oxygen therapy increases insulin sensitivity in obese individuals.
Intestinal Nutrient Sensing
  • Novel GI signalling pathways involved in the regulation of energy balance
  • Why do sweetened drinks link to type 2 diabetes?
  • Intestinal GLP-2 as a target in critical illness-induced malabsorption

GI Neuro-immune Interactions

  • Longitudinal study of immune activation in IBS
  • Faecal microbiota transplantation for UC
  • Next-Gen sequence of IBS patients; flare vs remission 

Visceral Pain

  • Itch specific pathways in the gut
  • Stable oxytocin analogues - potential treatment for IBS
  • GABA(B) Receptor Modulation of GI Function by Alpha-Conotoxins
  • Mechanisms of protease-driven visceral pain
  • Mechanisms and treatments for chronic visceral pain

Liver Metabolism

  • TRPM2 channels in oxidative stress-induced liver damage
  • Molecular mechanisms regulating Ca2+ channels formed by Orai and STIM proteins
  • A novel mechanism of ion channel regulation by oxygen 

Nutritional Epidemiology

  • Relationship between nutrients patterns, specific nutrients and subjective and objective sleep and disorders of sleep in men 
  • Health consequences of BPA and phthalate exposure
  • Nutrients patterns, specific nutrients and chronic disease/cancer risk and outcomes

Clinical Trials & Chronic Disease Epidemiology

  • Testosterone Prevention of T2DM in High Risk Men: A Randomized Placebo Controlled Trial (T4DM)
  • Exploiting alterations in lipid metabolism to improve diagnosis, treatment and molecular imaging of prostate cancer
  • LUTS as a marker and modifiable risk factor for cardio-metabolic disease
  • CRE in Translating Nutritional Science to Good Health 
Get in touch
+61 8 8128 4000 info@sahmri.com
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North Terrace Adelaide 5000 South Australia
Postal Address
PO BOX 11060 Adelaide 5001 South Australia
Key Partners
SAHMRI is located on the traditional lands of the Kaurna Nation.

The SAHMRI community acknowledges and respects the traditional owners, the family clans who are the Kaurna Nation from the Adelaide Plains region of South Australia. We acknowledge the clans of the Kaurna Nation and the sacred knowledge they hold for their country. We pay our respects to the Kaurna Nation, their ancestors and the descendants of these living family clans today.