The Hopwood Centre for Neurobiology (HCN) was launched on 26 October 2017. Formerly known as the Lysosomal Diseases Research Unit (LDRU), the change in name reflects a broadening of the Centre’s interests to investigate the role and function of the lysosome in late-onset neurodegeneration, such as Alzheimer’s. Joining SAHMRI in July 2013, the Centre supports a team of multidisciplinary and interactive biomedical researchers.
The importance of lysosomal biology to human health was first recognised in a group of inherited disorders known collectively as Lysosomal Storage Disorders (LSDs). The HCN has a proud track record of researching these disorders, from basic biology through to the development and commercialisation of treatment. Through these efforts, the HCN has been privileged to help improve the lives of affected individuals and their families.
More recently, increasing scientific evidence is implicating abnormal lysosomal function in areas of major community health concern, for instance some forms of heart disease, stroke, and neurodegenerative disorders (dementia and Alzheimer’s disease). Building on its years of experience in, and knowledge of, lysosomal biology, the HCN is breaking new ground in these important areas of health research.
The HCN comprises three research groups:
These groups are supported by two Core Facilities:
SAHMRI offers a unique opportunity to partner with world class researchers to identify new links and knowledge that can be applied to both prevention and treatment for these areas of pressing healthcare need.
The SAHMRI community acknowledges and respects the traditional owners, the family clans who are the Kaurna Nation from the Adelaide Plains region of South Australia. We acknowledge the clans of the Kaurna Nation and the sacred knowledge they hold for their country. We pay our respects to the Kaurna Nation, their ancestors and the descendants of these living family clans today.